Sulfadiazine plasma concentrations in women with pregnancy-acquired compared to ocular toxoplasmosis under pyrimethamine and sulfadiazine therapy: a case–control study
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منابع مشابه
Treating AIDS-associated cerebral toxoplasmosis - pyrimethamine plus sulfadiazine compared with cotrimoxazole, and outcome with adjunctive glucocorticoids.
We conducted a retrospective study of AIDS-associated cerebral toxoplasmosis. Eighteen patients received pyrimethamine plus sulfadiazine and 25 co-trimoxazole, with comparable baseline characteristics. There were no differences in clinical outcomes, but co-trimoxazole was better tolerated (p = 0.066). There was also a trend towards more deaths among patients who received glucocorticoids.
متن کاملShort-term Results of Two Treatment Regimens in Ocular Toxoplasmosis: Trimethoprim/Sulfamethoxazole versus Pyrimethamine and Sulfadiazine
Purpose: To compare the efficacy of classic treatment for ocular toxoplasmosis (pyrimethamine, sulfadiazine and predinsolone) with a regimen consisting of trimethoprim/sulfamethoxazole (TMP/SMX) [co-trimoxazole] plus predinsolone. Methods: In a prospective randomized single-blind clinical trial, 59 patients with active ocular toxoplasmosis were randomly assigned to two treatment groups: 29 were...
متن کاملIs Intravitreal Clindamycin, Dexamethasone Effective in Treating Ocular Toxoplasmosis? Randomized Trial of Intravitreal Clindamycin and Dexamethasone Versus Pyrimethamine, Sulfadiazine, and Prednisolone in Treatment of Ocular Toxoplasmosis
Participants/Methods: 68 patients with active ocular toxoplasmosis requiring therapy for vision-threatening disease were randomly assigned to 1 of 2 treatment groups. The intravitreal therapy group received an injection of clindamycin 1 mg and dexamethasone 400 μg administered at baseline and at 2 weekly intervals as needed according to response to initial therapy. Classic therapy consisted of ...
متن کاملAcquired ocular toxoplasmosis in pregnancy.
http://bjo.bmj.com/content/86/8/938.full.html Updated information and services can be found at: These include: References http://bjo.bmj.com/content/86/8/938.full.html#ref-list-1 This article cites 11 articles, 1 of which can be accessed free at: service Email alerting the top right corner of the online article. Receive free email alerts when new articles cite this article. Sign up in the box a...
متن کاملFailure of conventional treatment with pyrimethamine and sulfadiazine for secondary prophylaxis of cerebral toxoplasmosis in a patient with AIDS.
patient did not receive any medication known to alter the pharmacokinetics of levofloxacin. During levofloxacin treatment, renal function improved (creatinine clearance ¼102.3 mL/min) and glucose levels were unchanged. No electrocardiographic abnormalities or any adverse effect related to levofloxacin administration were found. The patient received this dose of intravenous levofloxacin for a to...
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ژورنال
عنوان ژورنال: European Journal of Medical Research
سال: 2020
ISSN: 2047-783X
DOI: 10.1186/s40001-020-00458-7